AOB2796
CAS No. 916170-19-9
AOB2796 ( AC-55541; AC 55541; AC55541 )
Catalog No. M17660 CAS No. 916170-19-9
AOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 77 | In Stock |
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10MG | 133 | In Stock |
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25MG | 228 | In Stock |
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50MG | 339 | In Stock |
|
100MG | 502 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameAOB2796
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NoteResearch use only, not for human use.
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Brief DescriptionAOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
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DescriptionAC-55541 is a protease-activated receptor (PAR) 2 agonist. AC-55541activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. AC-55541 was well absorbed when administered intraperitoneally to rats, each reaching micromolar peak plasma concentrations. AC-55541 was stable to metabolism by liver microsomes and maintained sustained exposure in rats, with elimination half-lives of 6.1. Systemic administration of either AC-55541 or AC-264613 produced a similar degree of hyperalgesia as was observed when the compounds were administered locally. AC-55541 may be useful in probing the physiological functions of PAR2 receptors.
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SynonymsAC-55541; AC 55541; AC55541
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PathwayOthers
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TargetOther Targets
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RecptorProtease-Activated Receptor 2
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number916170-19-9
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Formula Weight518.36
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Molecular FormulaC25H20BrN5O3
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Purity98%
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SolubilityDMSO : ≥ 51 mg/mL;;98.39 mM
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SMILESC/C(=N\NC(=O)C(c1n[nH]c(=O)c2ccccc12)NC(=O)c1ccccc1)/c1cc(ccc1)Br
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Chemical Name(E)-N-(2-(2-(1-(3-bromophenyl)ethylidene)hydrazinyl)-2-oxo-1-(4-oxo-3,4-dihydrophthalazin-1-yl)ethyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gardell LR, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808.
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