ANY1( FosA inhibitor ANY1 )

Catalog No. M14617 CAS No. 482574-02-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

ANY1
Note

Research use only, not for human use.
Brief Description

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA).
Description

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA); binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM; potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens.
In Vitro

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In Vivo

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Synonyms

FosA inhibitor ANY1
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

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Indication

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CAS Number

482574-02-7
Formula Weight

537.088
Molecular Formula

C15H7Br2N9O4
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

3-bromo-6-[3-(3-bromo-2-oxo-1H-pyrazolo[1,5-a]pyrimidin-6-yl)-4-nitro-1H-pyrazol-5-yl]-1H-pyrazolo[1,5-a]pyrimidin-2-one

1. Tomich AD, et al. Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01524-18.

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