ANT3310

CAS No. 2410688-61-6

ANT3310 ( —— )

Catalog No. M28513 CAS No. 2410688-61-6

ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 72 Get Quote
10MG 120 Get Quote
25MG 255 Get Quote
50MG 410 Get Quote
100MG 605 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ANT3310
  • Note
    Research use only, not for human use.
  • Brief Description
    ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection.
  • Description
    ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection.(In Vitro):ANT3310 shows a low in vitro cytotoxicity (IC50 > 100 μM), cardiotoxicity (inhibition of the hERG potassium ion channel) and genotoxicity in HepG2 cell. ANT3310 (0.006 to 3 000 nM) inhibits a series of Serine β-Lactamase including AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2, with IC<>50 values ranging from 1 nM to 175 nM.(In Vivo):In male Swiss albino mice, ANT3310 (1 mg/kg; i.v.) shows a T1/2 value of 0.64 h, AUC value of 412 ng?h/mL, and Cl value of 40 mL/min/kg. In the murine thigh infection model, ANT3310 (25, 50 and 100 mg/kg; i.v.) reduces bacterial burdens in a dose-dependent manner to levels below that of the initial starting inoculum at the highest dose, when treated with the combination of MEM.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2410688-61-6
  • Formula Weight
    263.2
  • Molecular Formula
    C6H9FN2NaO5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(S(=O)(=O)O)N1[C@H]2C[N@@](C1=O)[C@H](F)CC2.[Na]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • Sulfamoxole

    Sulfamoxole is an antibacterial belonging to sulfonamide.

  • Urechistachykinin II

    Urechistachykinin II (Uru-TK II) is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms.

  • Thimerosal

    Thimerosal is an organomercurial compound and derivative of thiosalicyclic acid with antibacterial and antifungal properties.