Cart
sales@molnova.com
AMPK-Activator-13
CAS No. 1243184-62-4
AMPK-Activator-13( MDK 4624 | AMPKα1 activator C13 | C13, Compound 13. )
Catalog No. M10984 CAS No. 1243184-62-4
A potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAMPK-Activator-13
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).
-
DescriptionA potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM); inhibits de novo lipogenesis in cellular and animal models of hyperlipidemia; the cell-permeable prodrug of compound 2 (AMPK-Activator-2).
-
In Vitro——
-
In Vivo——
-
SynonymsMDK 4624 | AMPKα1 activator C13 | C13, Compound 13.
-
PathwayMembrane Transporter/Ion Channel
-
TargetAMPK
-
RecptorAMPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1243184-62-4
-
Formula Weight431.334
-
Molecular FormulaC17H22NO10P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)C(OCOP(C1=CC=C(C(C2)=NOC2=O)O1)(OCOC(C(C)C)=O)=O)=O
-
Chemical Name(((5-(5-oxo-4,5-dihydroisoxazol-3-yl)furan-2-yl)phosphoryl)bis(oxy))bis(methylene) bis(2-methylpropanoate)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hunter RW, et al. Chem Biol. 2014 Jul 17;21(7):866-79.
2. Gómez-Galeno JE, et al. ACS Med Chem Lett. 2010 Aug 30;1(9):478-82.
molnova catalog
related products
-
Cimiracemoside C
Cimiracemoside C is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.
-
AMPK activator SC4
AMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3.
-
Onjisaponin B
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.
