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ALR2-IN-1

CAS No. 2799695-54-6

ALR2-IN-1( —— )

Catalog No. M36935 CAS No. 2799695-54-6

ALR2-IN-1 is a potent and selective ALR2 inhibitor with an IC50 value of 1.42 μM. ALR2-IN-1 possesses both antiglycemic and antioxidant activities and can be used to study the complications of diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ALR2-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    ALR2-IN-1 is a potent and selective ALR2 inhibitor with an IC50 value of 1.42 μM. ALR2-IN-1 possesses both antiglycemic and antioxidant activities and can be used to study the complications of diabetes.
  • Description
    ALR2-IN-1 is a potent and selective ALR2 inhibitor (IC50=1.42 μM). ALR2-IN-1 shows antioxidant and antiglycative properties. ALR2-IN-1 can be used in diabetic complication research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Reductase
  • Recptor
    Reductase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2799695-54-6
  • Formula Weight
    315.39
  • Molecular Formula
    C16H17N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (317.07 mM; Ultrasonic )
  • SMILES
    N(C(NN=CC1=C(O)C=CC(C)=C1)=S)C2=CC(OC)=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Aqeel Imran, et al. Development, Molecular Docking, and In Silico ADME Evaluation of Selective ALR2 Inhibitors for the Treatment of Diabetic Complications via Suppression of the Polyol Pathway. ACS Omega 2022.
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