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AKBA
CAS No. 67416-61-9
AKBA ( AKBA; 3-O-acetyl-11-keto-β-Boswellic acid )
Catalog No. M18980 CAS No. 67416-61-9
3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 1.5 m muM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 90 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAKBA
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NoteResearch use only, not for human use.
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Brief Description3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 1.5 m muM.
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DescriptionAKBA is an antiangiogenic and neuroprotective agent, reducing the impact of proliferative retinopathies, protecting neurons against ischemic injury involving the Nrf2/HO-1 pathway. It selectively inhibits 5-lipoxygenase (IC50 = 1.5 μM) in an enzyme-directed, nonredox, and noncompetitive manner.2 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.
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SynonymsAKBA; 3-O-acetyl-11-keto-β-Boswellic acid
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number67416-61-9
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Formula Weight512.73
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Molecular FormulaC32H48O5
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Purity98%
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SolubilityDMSO : ≥ 5.2 mg/mL; 10.14 mM
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SMILESCC1CCC2(CCC3(C(=CC(=O)C4C3(CCC5C4(CCC(C5(C)C(=O)O)OC(=O)C)C)C)C2C1C)C)C
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Chemical Name(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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WSB1 Degrader 1
WSB1 Degrader 1 is a poten and orally active?WD repeat and SOCS box-containing 1 degrader. WSB1 Degrader 1 has anticancer metastatic effects.
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(R)-3-Hydroxybutanoi...
3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone) levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis.
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Lupanine
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupanine improves glucose homeostasis by influencing KATP-channels of pancreatic beta cells.
