AK-778-XXMU

CAS No. 1227045-76-2

AK-778-XXMU( —— )

Catalog No. M35591 CAS No. 1227045-76-2

AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AK-778-XXMU
  • Note
    Research use only, not for human use.
  • Brief Description
    AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.
  • Description
    AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1227045-76-2
  • Formula Weight
    392.835
  • Molecular Formula
    C22H17ClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (254.56 mM; Ultrasonic )
  • SMILES
    O=C(C1=NC=CC=C1)CC2(O)C(=O)N(C=3C=CC=CC32)CC=4C=CC=C(Cl)C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhong G, et al. Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma. Bioorg Med Chem. 2021;49:116427. ?
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