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AGN192836

CAS No. 171102-29-7

AGN192836 ( AGN 192836 )

Catalog No. M12609 CAS No. 171102-29-7

AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    AGN192836
  • Note
    Research use only, not for human use.
  • Brief Description
    AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.
  • Description
    AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively; displays 1200-, 50- and 10-fols selectivity for the α2A-receptor, α2B-receptor, and α2C-receptors relative to the α2C-receptors; demonstrates effectivity for the reduction of intraocular pressure and for the reduction of blood pressure in vivo.
  • Synonyms
    AGN 192836
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    171102-29-7
  • Formula Weight
    231.26
  • Molecular Formula
    C12H13N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=C(C=CC2=C1OCCO2)NC3=NC=CN3
  • Chemical Name
    N-(2,3-Dihydro-5-methyl-1,4-benzodioxin-6-yl)-1H-imidazol-2-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Munk SA, et al. J Med Chem. 1997 Jan 3;40(1):18-23.
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