AG18

CAS No. 118409-57-7

AG18 ( RG-50810; RG-50858; TX 825; Tyrphostin 23; Tyrphostin AG-18 )

Catalog No. M10624 CAS No. 118409-57-7

AG-18(RG-50810; Tyrphostin A23) inhibits EGFR with IC50 of 35 μM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 49 In Stock
25MG 112 In Stock
50MG 212 In Stock
100MG 320 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AG18
  • Note
    Research use only, not for human use.
  • Brief Description
    AG-18(RG-50810; Tyrphostin A23) inhibits EGFR with IC50 of 35 μM.
  • Description
    AG-18(RG-50810; Tyrphostin A23) inhibits EGFR with IC50 of 35 μM.
  • Synonyms
    RG-50810; RG-50858; TX 825; Tyrphostin 23; Tyrphostin AG-18
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    118409-57-7
  • Formula Weight
    186.17
  • Molecular Formula
    C10H6N2O2
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 37 mg/mL (198.74 mM); DMSO: 37 mg/mL (198.74 mM)
  • SMILES
    N#C/C(C#N)=C/C1=CC=C(O)C(O)=C1
  • Chemical Name
    2-[(3,4-dihydroxyphenyl)methylene]-propanedinitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gazit A, et al. J Med Chem, 1989, 32(10), 2344-2352.
molnova catalog
related products
  • Erlotinib

    A potent, selective inhibitor of EGFR with IC50 of 2 nM; reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM.

  • JBJ-04-125-02

    JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities.

  • WHI-P258

    WHI-P258 is a dimethoxyquinazoline inhibitor of JAK3.