AG-270
CAS No. 2201056-66-6
AG-270 ( —— )
Catalog No. M28586 CAS No. 2201056-66-6
AG-270 is an allosteric and orally active inhibitor of MAT2A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 243 | Get Quote |
|
10MG | 389 | Get Quote |
|
25MG | 644 | Get Quote |
|
50MG | 888 | Get Quote |
|
100MG | 1233 | Get Quote |
|
500MG | 2457 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAG-270
-
NoteResearch use only, not for human use.
-
Brief DescriptionAG-270 is an allosteric and orally active inhibitor of MAT2A.
-
DescriptionAG-270 is an allosteric and orally active inhibitor of MAT2A.(In Vitro):AG-270 exhibits an IC50 of 20 nM in HCT116 MTAP-null cell SAM at 72 h.AG-270 demonstrates potent reduction in levels of intracellular SAM, as well as MTAP-null–selective antiproliferative activity in the HCT116 MTAP isogenic cell model in vitro.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2201056-66-6
-
Formula Weight489.6
-
Molecular FormulaC30H27N5O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOc(cc1)ccc1C(C(n1nc2-c3ccccc3)=O)=C(Nc3ncccc3)Nc1c2C1=CCCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Bagalagel, Alaa A.; Bogari, Hanin A.; Ahmed, Safwat A.; Diri, Reem M.; Elhady, Sameh S.[Heterocycles, 2018, vol. 96, # 4, p. 749 - 756]
molnova catalog
related products
-
IMM-01
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division.
-
Ganoderic acid DM
Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1).
-
Abaloparatide TFA (2...
Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 PTHR1 analogue and an effective and selective activator of the PTHR1 signaling pathway.