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AG-1478
CAS No. 153436-53-4
AG-1478 ( NSC 693255; Tyrphostin AG-1478 )
Catalog No. M12161 CAS No. 153436-53-4
AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 103 | In Stock |
|
| 50MG | 186 | In Stock |
|
| 100MG | 259 | In Stock |
|
| 200MG | 337 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAG-1478
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NoteResearch use only, not for human use.
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Brief DescriptionAG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.
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DescriptionAG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.
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SynonymsNSC 693255; Tyrphostin AG-1478
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR; HER2; PDGFR
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number153436-53-4
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Formula Weight315.75
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Molecular FormulaC16H14ClN3O2
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Purity>98%(HPLC)
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SolubilityEthanol: 13 mg/mL (41.17 mM); DMSO: 25 mg/mL (79.17 mM)
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SMILESCOC1=CC2=NC=NC(NC3=CC=CC(Cl)=C3)=C2C=C1OC
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Chemical NameN-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Levitzki A, et al. Science, 1995, 267(5205), 1782-1788.
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