AF-710B

CAS No. 1235733-73-9

AF-710B( —— )

Catalog No. M33961 CAS No. 1235733-73-9

AF-710B is a specific variant of M1 muscarinic and Sigma-1 receptor agonist used in the study of neurological disorders such as Alzheimer's disease dementia and schizophrenia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 506 Get Quote
5MG 751 Get Quote
10MG 1064 Get Quote
25MG 1536 Get Quote
50MG 2006 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AF-710B
  • Note
    Research use only, not for human use.
  • Brief Description
    AF-710B is a specific variant of M1 muscarinic and Sigma-1 receptor agonist used in the study of neurological disorders such as Alzheimer's disease dementia and schizophrenia.
  • Description
    AF710B is a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B can be used for the research of Alzheimer’s disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Sigma receptor
  • Recptor
    Sigma receptor | AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1235733-73-9
  • Formula Weight
    357.51
  • Molecular Formula
    C20H27N3OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N1CC2(SC1C)CCN(C)CC2)CCC3=CNC=4C=CC=CC43
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fisher A, et al. AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease. Neurodegener Dis. 2016;16(1-2):95-110.?
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