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AER-271
CAS No. 634913-39-6
AER-271 ( AER271 )
Catalog No. M15401 CAS No. 634913-39-6
AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 33 | In Stock |
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| 5MG | 53 | In Stock |
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| 10MG | 95 | In Stock |
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| 25MG | 205 | In Stock |
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| 50MG | 311 | In Stock |
|
| 100MG | 467 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAER-271
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NoteResearch use only, not for human use.
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Brief DescriptionAER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility.
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DescriptionAER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility; shows improved neurological outcome and reduced swelling in two models of CNS injury complicated by cerebral edema.Other Indication Phase 1 Clinical
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SynonymsAER271
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number634913-39-6
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Formula Weight463.65
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Molecular FormulaC15H9ClF6NO5P
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Purity>98% (HPLC)
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Solubility——
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SMILESO=P(O)(OC1=CC=C(Cl)C=C1C(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O)O
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Chemical Name2-{[3,5-Bis(trifluoromethyl) phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
2. Wallisch JS, et al. Pediatr Res. 2018 Oct 26. doi: 10.1038/s41390-018-0215-5.
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[Sar9,Met(O2)11]-Sub...
[Sar9,Met(O2)11]-Substance P TFA is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming.
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Geniposide
Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective,anti-diabetic,antiproliferative,and antioxidative activity.
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Heptanoic acid
Heptanoic acid is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid. It is an oily liquid with an unpleasant rancid odor. It contributes to the odor of some rancid oils. It is slightly soluble in water but well soluble in ethanol and ether.
