ACG-548B

CAS No. 795316-16-4

ACG-548B( ACG 548B )

Catalog No. M15978 CAS No. 795316-16-4

A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ACG-548B
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM.
  • Description
    A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ; demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 2.08 uM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ACG 548B
  • Pathway
    Others
  • Target
    ChoK
  • Recptor
    ChoK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    795316-16-4
  • Formula Weight
    777.426
  • Molecular Formula
    C38H34Br2Cl2N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C1=CC=[N+](CC2=CC(C3=CC=CC(C[N+]4=CC=C(N(C5=CC=C(Cl)C=C5)C)C=C4)=C3)=CC=C2)C=C1)C6=CC=C(Cl)C=C6.[Br-].[Br-]
  • Chemical Name
    1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)pyridin-1-ium) bromide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9. 2. Patent US 20110178124 A1. Pyridinium and quinolinium derivatives.
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