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AC1-IN-1
CAS No. 2762422-55-7
AC1-IN-1( —— )
Catalog No. M28481 CAS No. 2762422-55-7
AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 312 | Get Quote |
|
| 10MG | 500 | Get Quote |
|
| 25MG | 807 | Get Quote |
|
| 50MG | 1107 | Get Quote |
|
| 100MG | 1485 | Get Quote |
|
| 500MG | 2961 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAC1-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionAC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 μM).
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DescriptionAC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 μM).(In Vitro):In HEK293 cells, AC1-IN-1 (30 μM, 1 hours) shows nontoxic to this human cell line.(In Vivo):AC1-IN-1 (5.6 mg/kg; i.v.) displays modest, yet statistically significant, antiallodynic effects at 1 h post-treatment compared to the 0 min time point.
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In VitroAC1-IN-1 (compound 38; HEK293 cells; 30 μM, 1 hours) shows nontoxic to this human cell line.Cell Cytotoxicity Assay Cell Line:HEK293 cells Concentration:30 μM Incubation Time:1 hours Result:Showed nontoxic to HEK293 cells.
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In VivoAC1-IN-1 (5.6 mg/kg; i.v.) displays modest, yet statistically significant, antiallodynic effects at 1 h post-treatment compared to the 0 min (allodynic) time point. Animal Model:Male and female C57BL/6N mice (complete Freund’s adjuvant inflammatory pain model)Dosage:5.6 mg/kg (dissolved in 10% DMSO/10% Cremaphor/80% saline)Administration:Intravenous injection; 2 hours Result:Displayed modest, yet statistically significant, antiallodynic effects.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorApoptosis inhibitor
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Research Area——
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Indication——
Chemical Information
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CAS Number2762422-55-7
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Formula Weight355.37
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Molecular FormulaC18H18FN5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (70.35 mM)
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SMILESCCC1=CC(=O)N=C(N2N=C(C)C=C2NC(=O)C2=C(F)C=CC(C)=C2)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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