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AA92593

CAS No. 457961-34-1

AA92593( —— )

Catalog No. M22213 CAS No. 457961-34-1

AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AA92593
  • Note
    Research use only, not for human use.
  • Brief Description
    AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation.
  • Description
    AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation. Under this situation neither AANAT nor melatonin levels changed under light conditions . The discovery of melanopsin in the lens opens the possibility of regulating melatonin synthesis with the corresponding implication as an antioxidant substance.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    melanopsin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    457961-34-1
  • Formula Weight
    269.36
  • Molecular Formula
    C13H19NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccc(cc1C)[S](=O)(=O)N2CCCCC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Alkozi H A , Wang X , Jesus P D L M , et al. Presence of melanopsin in human crystalline lens epithelial cells and its role in melatonin synthesis[J]. Experimental Eye Research, 2016:168.
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