AA147

CAS No. 393121-74-9

AA147 ( ATF6-activator-147 )

Catalog No. M22642 CAS No. 393121-74-9

AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator.?The selectively activates ATF6 arm of the unfolded protein response (UPR) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 51 In Stock
10MG 87 In Stock
25MG 169 In Stock
50MG 251 In Stock
100MG 374 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AA147
  • Note
    Research use only, not for human use.
  • Brief Description
    AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator.?The selectively activates ATF6 arm of the unfolded protein response (UPR) .
  • Description
    AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator.?The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.
  • Synonyms
    ATF6-activator-147
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATF6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    393121-74-9
  • Formula Weight
    255.31
  • Molecular Formula
    C16H17NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Christina COOLEY, et al. Regulators of the endoplasmic reticulum proteostasis network. WO2017117430A1.
molnova catalog
related products
  • GIP (1-30) amide (Hu...

    GIP (1-30) amide (Human) TFA is a glucose-dependent insulinotropic polypeptide fragment. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions.

  • Angelicain

    Angelicain is a constituent of Cimicifuga foetida with anti-inflammatory activity.

  • Isoscoparin-2-Beta-D...

    Isoscoparin-2''-Beta-D-glucopyranoside shows prominent free radical scavenging activity in DPPH assay.