A-867744

CAS No. 1000279-69-5

A-867744( —— )

Catalog No. M23206 CAS No. 1000279-69-5

A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 In Stock
5MG 58 In Stock
10MG 87 In Stock
25MG 174 In Stock
50MG 312 In Stock
100MG 467 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    A-867744
  • Note
    Research use only, not for human use.
  • Brief Description
    A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
  • Description
    A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy|α7 nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1000279-69-5
  • Formula Weight
    402.89
  • Molecular Formula
    C20H19ClN2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (248.21 mM)
  • SMILES
    CCC(c(cc1-c(cc2)ccc2Cl)c(C)n1-c(cc1)ccc1S(N)(=O)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Malysz J, et al. In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile. J Pharmacol Exp Ther. 2009 Jul;330(1):257-67.
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