8-Geranyloxypsoralen

CAS No. 7437-55-0

8-Geranyloxypsoralen( —— )

Catalog No. M24753 CAS No. 7437-55-0

8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    8-Geranyloxypsoralen
  • Note
    Research use only, not for human use.
  • Brief Description
    8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues.
  • Description
    8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    Anti-infection|BACE|P450
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7437-55-0
  • Formula Weight
    338.4
  • Molecular Formula
    C21H22O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (295.51 mM)
  • SMILES
    CC(C)=CCCC(C)=CCOc(c(occ1)c1cc1C=C2)c1OC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nematicidal coumarins from Heracleum candicans Wall.Nat Prod Res. 2008 May 20;22(8):666-71.
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