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7-Hydroxycarbostyril
CAS No. 70500-72-0
7-Hydroxycarbostyril( 3,4-Dihydro-7-hydroxycarbostyril )
Catalog No. M27524 CAS No. 70500-72-0
7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 46 | In Stock |
|
| 25MG | 70 | In Stock |
|
| 50MG | 106 | In Stock |
|
| 100MG | 158 | In Stock |
|
| 200MG | 239 | In Stock |
|
| 500MG | 357 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name7-Hydroxycarbostyril
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NoteResearch use only, not for human use.
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Brief Description7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.
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Description7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.(In Vitro):?VPC-80051 as the first small molecule inhibitor of hnRNP A1 splicing activity discovered to date by using a computer-aided drug discovery approach. The inhibitor was developed to target the RNA-binding domain (RBD) of hnRNP A1. Further experimental evaluation demonstrated that VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. This study lays the groundwork for future structure-based development of more potent and selective small molecule inhibitors of hnRNP A1?RNA interactions aimed at altering the production of cancer-specific alternative splice isoforms.
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In Vitro——
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In Vivo——
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Synonyms3,4-Dihydro-7-hydroxycarbostyril
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PathwayOthers
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TargetOther Targets
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RecptorTRPA1
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Research Area——
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Indication——
Chemical Information
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CAS Number70500-72-0
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Formula Weight161.16
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Molecular FormulaC9H7NO2
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Purity>98% (HPLC)
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Solubility——
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SMILESOc1ccc2ccc(O)nc2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Takaya J, et al. A Potent and Site-Selective Agonist of TRPA1. J Am Chem Soc. 2015 Dec 23;137(50):15859-64.
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