7-Hydroxycarbostyril

CAS No. 70500-72-0

7-Hydroxycarbostyril ( 3,4-Dihydro-7-hydroxycarbostyril )

Catalog No. M27524 CAS No. 70500-72-0

7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 46 In Stock
25MG 70 In Stock
50MG 106 In Stock
100MG 158 In Stock
200MG 239 In Stock
500MG 357 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    7-Hydroxycarbostyril
  • Note
    Research use only, not for human use.
  • Brief Description
    7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.
  • Description
    7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) is a kind of pharmaceutical intermediate.(In Vitro):?VPC-80051 as the first small molecule inhibitor of hnRNP A1 splicing activity discovered to date by using a computer-aided drug discovery approach. The inhibitor was developed to target the RNA-binding domain (RBD) of hnRNP A1. Further experimental evaluation demonstrated that VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. This study lays the groundwork for future structure-based development of more potent and selective small molecule inhibitors of hnRNP A1?RNA interactions aimed at altering the production of cancer-specific alternative splice isoforms.
  • Synonyms
    3,4-Dihydro-7-hydroxycarbostyril
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TRPA1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    70500-72-0
  • Formula Weight
    161.2
  • Molecular Formula
    C9H7NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Oc1ccc2ccc(O)nc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Takaya J, et al. A Potent and Site-Selective Agonist of TRPA1. J Am Chem Soc. 2015 Dec 23;137(50):15859-64.
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