7-Chloro-4-(piperazin-1-yl)quinoline

Research use only, not for human use.

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry, exhibiting diverse pharmacological profiles either alone or as a hybrid with other active pharmacophores.

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is apotent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively.

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Others

Other Targets

Others

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837-52-5

247.72

C13H14ClN3

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (201.84 mM; Ultrasonic)

ClC1=CC2=NC=CC(N3CCNCC3)=C2C=C1

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(-20℃)

With Ice Pack

≥ 2 years