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7-Acetoxy-4-methylcoumarin

CAS No. 2747-05-9

7-Acetoxy-4-methylcoumarin ( —— )

Catalog No. M19337 CAS No. 2747-05-9

7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage.

Purity : 95%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    7-Acetoxy-4-methylcoumarin
  • Note
    Research use only, not for human use.
  • Brief Description
    7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage.
  • Description
    7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin, the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2747-05-9
  • Formula Weight
    218.21
  • Molecular Formula
    C12H10O4
  • Purity
    95%
  • Solubility
    ——
  • SMILES
    CC(=O)Oc1ccc2c(c1)OC(=O)C=C2C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Berman HA,et al.Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.Mol Pharmacol. 1992 Feb;41(2):412-8.
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