6RK73
CAS No. 1895050-66-4
6RK73 ( —— )
Catalog No. M26038 CAS No. 1895050-66-4
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 282 | Get Quote |
|
10MG | 483 | Get Quote |
|
25MG | 782 | Get Quote |
|
50MG | 1071 | Get Quote |
|
100MG | 1431 | Get Quote |
|
500MG | 2898 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product Name6RK73
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NoteResearch use only, not for human use.
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Brief Description6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM).
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Description6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 μM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 μM).(In Vitro):6RK73 (5 μM; 1-3 hours) treatment displays strong inhibition of the TGFβ-induced pSMAD2 and pSMAD3, and a decrease of TβRI and total SMAD protein levels in MDA-MB-436 cells. 6RK73 (5 μM; 24-48 hours) results in migration significantly slower than the DMSO control group in MDA-MB-436 cells.(In Vivo):6RK73 displays a potent inhibition of breast cancer extravasation in zebrafish.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAntioxidant
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Research Area——
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Indication——
Chemical Information
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CAS Number1895050-66-4
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Formula Weight307.4
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Molecular FormulaC13H17N5O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(Nc1ncc(s1)N1CCOCC1)[C@H]1CCN(C1)C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Safranal Attenuates Excitotoxin-Induced Oxidative OLN-93 Cells Injury
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