6-Thio-dG ( 6-thio-dG; 6thiodG; 6 thio dG; 6-Thio-2'-deoxyguanosine )

Catalog No. M19108 CAS No. 789-61-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

6-Thio-dG
Note

Research use only, not for human use.
Brief Description

6-thio-dG is a nucleoside analog and telomerase substrate.
Description

6-thio-dG is a telomerase substrate precursor with anticancer activities. In A549 lung cancer cell-based mouse xenograft studies, 6-thio-dG caused a decrease in the tumor growth rate superior to that observed with 6-thioguanine treatment. In addition, 6-thio-dG increased telomere dysfunction in tumor cells in vivo.
Synonyms

6-thio-dG; 6thiodG; 6 thio dG; 6-Thio-2'-deoxyguanosine
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

789-61-7
Formula Weight

283.31
Molecular Formula

C10H13N5O3S
Purity

98%
Solubility

DMSO : ≥ 130 mg/mL; 458.86 mM
SMILES

NC1=NC(=S)C2=C(N1)N(C=N2)[C@H]1C[C@H](O)[C@@H](CO)O1
Chemical Name

2-Amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione