6-Methylflavone
CAS No. 29976-75-8
6-Methylflavone( —— )
Catalog No. M21420 CAS No. 29976-75-8
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | 37 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name6-Methylflavone
-
NoteResearch use only, not for human use.
-
Brief Description6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
-
Description6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
-
In Vitro6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α1β2γ2L and α1β2 GABAA receptors (P<0.0001) at concentrations from 1 to 100 μM. 6-Methylflavone (60 μM) shifts the GABA dose-response curve to the left (n=4, F=16.38, P=0.0004), decreasing the mean EC50 at α1β2γ2L GABAA receptors by 33±5.4%.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptorα1β2γ2L GABAA receptor|α1β2 GABAA receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number29976-75-8
-
Formula Weight236.27
-
Molecular FormulaC16H12O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:5 mg/mL (211.62 mM)
-
SMILESCC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hall BJ et al. Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors. Eur J Pharmacol. 2004 Apr 26;491(1):1-8.
molnova catalog
related products
-
Cyclic MKEY TFA (934...
Cyclic MKEY TFA is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation.
-
Magnoloside A
Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml.
-
Cortistatin-14 TFA (...
Cortistatin-14 is a neuropeptide have structural similarity to somatostatin-14. It is produced in the cortex and hippocampus of central nervous system.