6-Diazo-5-oxo-L-nor-Leucine ( L-6-Diazo-5-oxonorleucine;DON;Diazooxonorleucine )

Catalog No. M21634 CAS No. 157-03-9

L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

6-Diazo-5-oxo-L-nor-Leucine
Note

Research use only not for human use.
Brief Description

L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
Description

L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
Synonyms

L-6-Diazo-5-oxonorleucine;DON;Diazooxonorleucine
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Glutaminase;Bacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

157-03-9
Formula Weight

171.15
Molecular Formula

C6H9N3O3?
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Willis RC et al. The inhibition by 6-diazo-5-oxo-l-norleucine of glutamine catabolism of the cultured human lymphoblast. J Cell Physiol. 1977 Dec;93(3):375-82.

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