6-Diazo-5-oxo-L-nor-Leucine

CAS No. 157-03-9

6-Diazo-5-oxo-L-nor-Leucine ( L-6-Diazo-5-oxonorleucine;DON;Diazooxonorleucine )

Catalog No. M21634 CAS No. 157-03-9

L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 401 Get Quote
10MG 601 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    6-Diazo-5-oxo-L-nor-Leucine
  • Note
    Research use only not for human use.
  • Brief Description
    L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
  • Description
    L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
  • Synonyms
    L-6-Diazo-5-oxonorleucine;DON;Diazooxonorleucine
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Glutaminase;Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    157-03-9
  • Formula Weight
    171.15
  • Molecular Formula
    C6H9N3O3?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Willis RC et al. The inhibition by 6-diazo-5-oxo-l-norleucine of glutamine catabolism of the cultured human lymphoblast. J Cell Physiol. 1977 Dec;93(3):375-82.
molnova catalog
related products
  • Calcimycin

    Calcimycin is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis.?It binds and transports calcium and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria.?The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.?

  • 4-Hydroxy-25-dimethy...

    4-Hydroxy-25-dimethyl-3(2H)furanone is a naturally occurring substance found in a variety of fruits. It has been shown to have antimicrobial activity.

  • Antibiotic-5d

    A synthetic antimicrobial compound that antibacterial activity in vitro against various Gram-positive and Gram-negative bacteria, fungi and yeast.