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Home - Products - GPCR/G Protein - Antibacterial - 6-Diazo-5-oxo-L-nor-Leucine

6-Diazo-5-oxo-L-nor-Leucine

CAS No. 157-03-9

6-Diazo-5-oxo-L-nor-Leucine ( L-6-Diazo-5-oxonorleucine;DON;Diazooxonorleucine )

Catalog No. M21634 CAS No. 157-03-9

L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    6-Diazo-5-oxo-L-nor-Leucine
  • Note
    Research use only not for human use.
  • Brief Description
    L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
  • Description
    L-6-Diazo-5-oxonorleucine is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
  • Synonyms
    L-6-Diazo-5-oxonorleucine;DON;Diazooxonorleucine
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Glutaminase;Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    157-03-9
  • Formula Weight
    171.15
  • Molecular Formula
    C6H9N3O3?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Willis RC et al. The inhibition by 6-diazo-5-oxo-l-norleucine of glutamine catabolism of the cultured human lymphoblast. J Cell Physiol. 1977 Dec;93(3):375-82.
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