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5-hydroxytryptamine
CAS No. 50-67-9
5-hydroxytryptamine( —— )
Catalog No. M24470 CAS No. 50-67-9
5-hydroxytryptamine is a natural product from animals.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 411 | In Stock |
|
| 10MG | 616 | In Stock |
|
| 25MG | 981 | In Stock |
|
| 50MG | 1332 | In Stock |
|
| 100MG | 1791 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name5-hydroxytryptamine
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NoteResearch use only, not for human use.
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Brief Description5-hydroxytryptamine is a natural product from animals.
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Description5-hydroxytryptamine is a natural product from animals.
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In VitroSerotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin also inhibits catechol O-methyltransferase (COMT), an enzyme that contributes to modultion the perception of pain, via non-competitive binding to the site bound by catechol substrates with a binding affinity comparable to the binding affinity of catechol itself (Ki=?44 μM). Results show that addition of 100 μM of Serotonin decreases the reaction velocity of COMT.
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In VivoSerotonin produces robust hypersensitivity compare to saline-treated controls (p<0.001). A significant increase in colonic 5-HT content is observed in IL-13-/- mice receiving Serotonin compare to IL-13-/- receiving vehicle following induction of DSS colitis.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number50-67-9
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Formula Weight176.22
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Molecular FormulaC10H12N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (567.47 mM)
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SMILESNCCc1c[nH]c(cc2)c1cc2O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sigal Rozenblit㏒usan, Chapnik N , Froy O . Serotonin Prevents Differentiation of Brown Adipocytes by Interfering with Their Clock[J]. Obesity, 2019, 27(12).
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