5-Methylcytosine

CAS No. 554-01-8

5-Methylcytosine ( —— )

Catalog No. M20002 CAS No. 554-01-8

5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants the methylated sequence is CpNpGp where N can be any base. 5-Methylcytosine is an epigenetic modification formed by the action of DNA methyltransferases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-Methylcytosine
  • Note
    Research use only not for human use.
  • Brief Description
    5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants the methylated sequence is CpNpGp where N can be any base. 5-Methylcytosine is an epigenetic modification formed by the action of DNA methyltransferases.
  • Description
    5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants the methylated sequence is CpNpGp where N can be any base. 5-Methylcytosine is an epigenetic modification formed by the action of DNA methyltransferases. In bacteria 5-methylcytosine can be found at a variety of sites and is often used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    554-01-8
  • Formula Weight
    125.13
  • Molecular Formula
    C5H7N3O
  • Purity
    >98% (HPLC)
  • Solubility
    Water:63.9 mM
  • SMILES
    Cc1c[nH]c(=O)nc1N
  • Chemical Name
    4-amino-5-methylpyrimidin-2(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pfeifer GP et al. Mutations induced by ultraviolet light. Mutat Res. 2005 Apr 1;571(1-2):19-31.
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