5-Methylcytosine ( —— )

Catalog No. M20002 CAS No. 554-01-8

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Product Name

5-Methylcytosine
Note

Research use only not for human use.
Brief Description

5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants the methylated sequence is CpNpGp where N can be any base. 5-Methylcytosine is an epigenetic modification formed by the action of DNA methyltransferases.
Description

5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants the methylated sequence is CpNpGp where N can be any base. 5-Methylcytosine is an epigenetic modification formed by the action of DNA methyltransferases. In bacteria 5-methylcytosine can be found at a variety of sites and is often used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes.
Synonyms

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Pathway

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Research Area

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Indication

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1.Pfeifer GP et al. Mutations induced by ultraviolet light. Mutat Res. 2005 Apr 1;571(1-2):19-31.

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