5-Geranoxy-7-methoxycoumarin

CAS No. 7380-39-4

5-Geranoxy-7-methoxycoumarin( —— )

Catalog No. M24746 CAS No. 7380-39-4

5-Geranoxy-7-methoxycoumarin shows antifungal activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 231 In Stock
10MG 342 In Stock
25MG 574 In Stock
50MG 801 In Stock
100MG 1107 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    5-Geranoxy-7-methoxycoumarin
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Geranoxy-7-methoxycoumarin shows antifungal activity.
  • Description
    5-Geranoxy-7-methoxycoumarin shows antifungal activity.
  • In Vitro
    5-Geranoxy-7-methoxycoumarin (12.5-200 μM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells.5-Geranoxy-7-methoxycoumarin (50 μM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation.Cell Proliferation Assay Cell Line:SW480 Concentration:0-20 μM Incubation Time:24, 48 and 72 hours Result:Inhibited cell growth by 67% at 72 hours.Apoptosis Analysis Cell Line:SW480 cells Concentration:50 μM Incubation Time:48 hours Result:Induced cell apoptosis.Cell Cycle Analysis Cell Line:SW480 cells Concentration:50 μM Incubation Time:48 hours Result:Inhibited cell cycle progression in vitro.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    Anti-infection
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7380-39-4
  • Formula Weight
    328.4
  • Molecular Formula
    C20H24O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC(=CCCC(=CCOC1=CC(=CC2=C1C=CC(=O)O2)OC)C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Preformed and induced antifungal materials of citrus fruits in relation to the enhancement of decay resistance by heat and ultraviolet treatments. Journal of Agricultural and Food Chemistry, 1992, 40(7):1217-1221.
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