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5-DEMETHYLNOBILETIN

CAS No. 2174-59-6

5-DEMETHYLNOBILETIN( 5-O-Demethylnobiletin )

Catalog No. M20414 CAS No. 2174-59-6

5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 197 In Stock
25MG 345 In Stock
50MG 482 In Stock
100MG 716 In Stock
500MG 1557 In Stock
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Biological Information

  • Product Name
    5-DEMETHYLNOBILETIN
  • Note
    Research use only, not for human use.
  • Brief Description
    5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.
  • Description
    5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.
  • In Vitro
    5-O-Demethylnobiletin (5-demethylnobiletin) promotes neuritogenesis through the activation of MAPK/ERK-, PKC-, and PKA-dependent signaling pathways.
  • In Vivo
    ——
  • Synonyms
    5-O-Demethylnobiletin
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    LOX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2174-59-6
  • Formula Weight
    388.37
  • Molecular Formula
    C20H20O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:32 mg/mL (82.39 mM)
  • SMILES
    COc1ccc(cc1OC)-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1
  • Chemical Name
    2-(34-Dimethoxyphenyl)-5-hydroxy-678-trimethoxychromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells.
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