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5-A-RU-PABC-Val-Cit-Fmoc

CAS No. 2677841-58-4

5-A-RU-PABC-Val-Cit-Fmoc( —— )

Catalog No. M35200 CAS No. 2677841-58-4

5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    5-A-RU-PABC-Val-Cit-Fmoc
  • Note
    Research use only, not for human use.
  • Brief Description
    5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.
  • Description
    5-A-RU-PABC-Val-Cit-Fmoc is the proagent of 5-A-RU. 5-A-RU, a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules, such as glyoxal and methylglyoxal, which are derived from other metabolic pathways.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2677841-58-4
  • Formula Weight
    903.93
  • Molecular Formula
    C43H53N9O13
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 150 mg/mL (165.94 mM; Ultrasonic )
  • SMILES
    CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Nc2c(NC[C@H](O)[C@H](O)[C@H](O)CO)[nH]c(=O)[nH]c2=O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Joshua Lange, et al. The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes. ACS Chem Biol. 2020 Feb 21;15(2):437-445.?
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