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5-(Hydroxymethyl)uracil

CAS No. 4433-40-3

5-(Hydroxymethyl)uracil ( 5-Hydroxymethyluracil;Hydroxymethyl Uracil;a-Hydroxythymine )

Catalog No. M20049 CAS No. 4433-40-3

5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-(Hydroxymethyl)uracil
  • Note
    Research use only not for human use.
  • Brief Description
    5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.
  • Description
    5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.
  • Synonyms
    5-Hydroxymethyluracil;Hydroxymethyl Uracil;a-Hydroxythymine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4433-40-3
  • Formula Weight
    142.11
  • Molecular Formula
    C5H6N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 50 mg/mL;Water: 15 mg/mL
  • SMILES
    OCc1c[nH]c(=O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kow YW. Repair of deaminated bases in DNA. Free Radic Biol Med. 2002 Oct 1;33(7):886-93.
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