5-(Hydroxymethyl)uracil

CAS No. 4433-40-3

5-(Hydroxymethyl)uracil ( 5-Hydroxymethyluracil;Hydroxymethyl Uracil;a-Hydroxythymine )

Catalog No. M20049 CAS No. 4433-40-3

5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1G 43 In Stock

Biological Information

  • Product Name
    5-(Hydroxymethyl)uracil
  • Note
    Research use only not for human use.
  • Brief Description
    5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.
  • Description
    5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hydroxymethyluracil are formed when cells are under oxidative stress that is induced either by oxidizing agents or by mitochondrial dysfunction.
  • Synonyms
    5-Hydroxymethyluracil;Hydroxymethyl Uracil;a-Hydroxythymine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4433-40-3
  • Formula Weight
    142.11
  • Molecular Formula
    C5H6N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 50 mg/mL;Water: 15 mg/mL
  • SMILES
    OCc1c[nH]c(=O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kow YW. Repair of deaminated bases in DNA. Free Radic Biol Med. 2002 Oct 1;33(7):886-93.
molnova catalog
related products
  • Cyclo(D-Phe-L-Pro)

    Cyclo(D-Phe-L-Pro) is a natural product from Phellinus igniarius.

  • GNF351

    GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity.?GNF351 is minimal toxicity in mouse or human keratinocytes.?

  • Coptisine

    Coptisine treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase.