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4u8C
CAS No. 14003-96-4
4u8C( IRE1 Inhibitor III )
Catalog No. M11667 CAS No. 14003-96-4
4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 52 | In Stock |
|
| 25MG | 88 | In Stock |
|
| 50MG | 138 | In Stock |
|
| 100MG | 210 | In Stock |
|
| 500MG | 525 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4u8C
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NoteResearch use only, not for human use.
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Brief Description4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
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Description4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
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In Vitro——
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In VivoAnimal Model:ApoE-/- mice Dosage:10 mg/kg Administration:I.p. injection; daily; for 4 more weeks Result:Led to a significant reduction (45.2%) in atherosclerotic lesion area in en face aorta preparations.
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SynonymsIRE1 Inhibitor III
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PathwayOthers
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TargetOther Targets
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RecptorIRE1 RN/Ase
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number14003-96-4
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Formula Weight204.18
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Molecular FormulaC11H8O4
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Purity>98% (HPLC)
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SolubilityDMSO:19 mg/mL (93.05 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
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SMILESO=CC1=C(O2)C(C(C)=CC2=O)=CC=C1O
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Chemical Name7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cross BC, et al. Proc natl Acad Sci U S A. 2012, 109(15), E869-878.
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