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4-methoxylonchocarpin
CAS No. 51589-67-4
4-methoxylonchocarpin( —— )
Catalog No. M37846 CAS No. 51589-67-4
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 466 | Get Quote |
|
| 10MG | 679 | Get Quote |
|
| 25MG | 1003 | Get Quote |
|
| 50MG | 1362 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name4-methoxylonchocarpin
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NoteResearch use only, not for human use.
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Brief Description4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
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Description4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB | TNF
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Research Area——
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Indication——
Chemical Information
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CAS Number51589-67-4
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Formula Weight336.38
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Molecular FormulaC21H20O4
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Purity>98% (HPLC)
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Solubility——
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SMILESOC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jang HM, et al. 4-Methoxylonchocarpin attenuates inflammation by inhibiting lipopolysaccharide binding to Toll-like receptor of macrophages and M1 macrophage polarization. Int Immunopharmacol. 2017 Apr;45:90-97.?
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