Cart
sales@molnova.com
4-methoxylonchocarpin
CAS No. 51589-67-4
4-methoxylonchocarpin( —— )
Catalog No. M37846 CAS No. 51589-67-4
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 466 | Get Quote |
|
| 10MG | 679 | Get Quote |
|
| 25MG | 1003 | Get Quote |
|
| 50MG | 1362 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name4-methoxylonchocarpin
-
NoteResearch use only, not for human use.
-
Brief Description4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
-
Description4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB | TNF
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number51589-67-4
-
Formula Weight336.38
-
Molecular FormulaC21H20O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jang HM, et al. 4-Methoxylonchocarpin attenuates inflammation by inhibiting lipopolysaccharide binding to Toll-like receptor of macrophages and M1 macrophage polarization. Int Immunopharmacol. 2017 Apr;45:90-97.?
molnova catalog
related products
-
Epoxyazadiradione
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.
-
1-Caffeoylquinic aci...
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis.
-
Tomatidine
Tomatidine decreases inducible NO synthase and COX-2 expression through suppression of I-κBα phosphorylation, NF-κB nuclear translocation and JNK activation, which in turn inhibits c-jun phosphorylation and Oct-2 expression.
