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4-Hydroxybenzylamine

CAS No. 696-60-6

4-Hydroxybenzylamine ( 4-HOBA; 4-(Aminomethyl)phenol; 4-Hydroxybenzylamine )

Catalog No. M27368 CAS No. 696-60-6

4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    4-Hydroxybenzylamine
  • Note
    Research use only, not for human use.
  • Brief Description
    4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.
  • Description
    4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.(In Vivo):4-HOBA attenuated the left ventricular (LV) and lung IsoLGs in mice after TAC. 4-HOBA attenuated TAC-induced LV hypertrophy, heart failure, and the increase of lung weight in mice, and also improved TAC-induced LV dysfunction. Moreover, 4-HOBA effectively attenuated LV cardiomyocyte hypertrophy, lung inflammation, lung fibrosis.
  • Synonyms
    4-HOBA; 4-(Aminomethyl)phenol; 4-Hydroxybenzylamine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    696-60-6
  • Formula Weight
    123.2
  • Molecular Formula
    C7H9NO
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NCc1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Furukawa T, Sakamoto N, Suzuki M, Kimura M, Nagasawa H, Sakuda S. Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum. PLoS One. 2015 Aug 6;10(8):e0135031. doi: 10.1371/journal.pone.0135031. eCollection 2015. PubMed PMID: 26248339; PubMed Central PMCID: PMC4527739.
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