4-CPPC

CAS No. 29553-70-6

4-CPPC ( —— )

Catalog No. M28169 CAS No. 29553-70-6

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 110 Get Quote
10MG 178 Get Quote
25MG 410 Get Quote
50MG 605 Get Quote
100MG 860 Get Quote
500MG 1728 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    4-CPPC
  • Note
    Research use only, not for human use.
  • Brief Description
    4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).
  • Description
    4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PXR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    29553-70-6
  • Formula Weight
    287.2
  • Molecular Formula
    C14H9NO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)c1cccc(c1)-c1cc(ncc1C(O)=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lin W, et, al. SPA70 is a potent antagonist of human pregnane X receptor. Nat Commun. 2017 Sep 29;8(1):741.
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