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3-Deoxy-3-fluoroadenosine
CAS No. 75059-22-2
3-Deoxy-3-fluoroadenosine( —— )
Catalog No. M37870 CAS No. 75059-22-2
3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with broad anti-tumor and anti-viral activity, showing inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus, and West Nile virus (WNV) with EC50 values of 1.1 μM, 0.1 μM and [4.7 ± 1.5] μM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
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| 10MG | 48 | In Stock |
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| 25MG | 98 | In Stock |
|
| 50MG | 158 | In Stock |
|
| 100MG | 249 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name3-Deoxy-3-fluoroadenosine
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NoteResearch use only, not for human use.
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Brief Description3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with broad anti-tumor and anti-viral activity, showing inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus, and West Nile virus (WNV) with EC50 values of 1.1 μM, 0.1 μM and [4.7 ± 1.5] μM, respectively.
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Description3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorNucleoside Antimetabolite/Analog
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Research Area——
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Indication——
Chemical Information
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CAS Number75059-22-2
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Formula Weight269.23
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Molecular FormulaC10H12FN5O3
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Purity>98% (HPLC)
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Solubility——
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SMILESNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](F)[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?
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