3-Bromocytisine( 3-Br-cytisine | (-)-3-Bromocytisine | (-)-9-Bromocytisine )

Catalog No. M26025 CAS No. 207390-14-5

3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

3-Bromocytisine
Note

Research use only, not for human use.
Brief Description

3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh).
Description

3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh).(In Vitro):3-Bromocytisine shows different effects on high and low ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively .
In Vitro

——
In Vivo

——
Synonyms

3-Br-cytisine | (-)-3-Bromocytisine | (-)-9-Bromocytisine
Pathway

Others
Target

Other Targets
Recptor

D4
Research Area

——
Indication

——

Chemical Information

CAS Number

207390-14-5
Formula Weight

269.142
Molecular Formula

C11H13BrN2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (371.55 mM)
SMILES

Brc1ccc2[C@H]3CNC[C@H](C3)Cn2c1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Nakazawa S, et al. Behavioral and neurophysiological effects of Ro 10-5824, a dopamine D4 receptor partial agonist, in common marmosets. Psychopharmacology (Berl). 2015 Sep;232(17):3287-95.

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