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3-Bromocytisine

CAS No. 207390-14-5

3-Bromocytisine ( 3-Br-cytisine; (-)-3-Bromocytisine; (-)-9-Bromocytisine )

Catalog No. M26025 CAS No. 207390-14-5

3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-Bromocytisine
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh).
  • Description
    3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh).(In Vitro):3-Bromocytisine shows different effects on high and low ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively .
  • Synonyms
    3-Br-cytisine; (-)-3-Bromocytisine; (-)-9-Bromocytisine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    D4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    207390-14-5
  • Formula Weight
    269.1
  • Molecular Formula
    C11H13BrN2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Brc1ccc2[C@H]3CNC[C@H](C3)Cn2c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nakazawa S, et al. Behavioral and neurophysiological effects of Ro 10-5824, a dopamine D4 receptor partial agonist, in common marmosets. Psychopharmacology (Berl). 2015 Sep;232(17):3287-95.
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