25-Hydroxycholesterol

CAS No. 2140-46-7

25-Hydroxycholesterol ( —— )

Catalog No. M19577 CAS No. 2140-46-7

25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 41 In Stock
10MG 55 In Stock
25MG 84 In Stock
50MG 128 In Stock
100MG 201 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    25-Hydroxycholesterol
  • Note
    Research use only not for human use.
  • Brief Description
    25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs).
  • Description
    25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regulation of cholesterol biosynthesis after an acute dietary cholesterol challenge. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    other; HMG-CoA Reductase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2140-46-7
  • Formula Weight
    402.65
  • Molecular Formula
    C27H46O2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 20 mg/mL;Chloroform: 50 mg/mL
  • SMILES
    C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.McDonald JG et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2.
molnova catalog
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