21-deacetyldeflazacort

Research use only, not for human use.

21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.

21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.(In Vitro):21-deacetyldeflazacort displaces [3H]dexamethasone from its cytosol receptor sites in rat kidney, thymus and liver in vitro.(In Vivo):21-deacetyldeflazacort inhibited 48-h homologous passive cutaneous anaphylaxis in rats, but had no significant effects on active systemic anaphylaxis in mice, on the Schultz-Dale reaction in the isolated guinea-pig trachea or on compound 48/80-induced histamine release in rat peritoneal mast cells. 21-deacetyldeflazacort inhibited reversed cutaneous anaphylaxis in rats and the Arthus reaction in mice.

——

Others

Other Targets

——

——

——

13649-57-5

399.5

C23H29NO5

>98% (HPLC)

——

CC1=N[C@@]2([C@@H](C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C)O1)C(=O)CO

——

(-20℃)

With Ice Pack

≥ 2 years