
20(S)-Hydroxycholesterol
CAS No. 516-72-3
20(S)-Hydroxycholesterol( —— )
Catalog No. M32745 CAS No. 516-72-3
20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 46 | In Stock |
![]() ![]() |
5MG | 72 | In Stock |
![]() ![]() |
10MG | 122 | In Stock |
![]() ![]() |
25MG | 256 | In Stock |
![]() ![]() |
50MG | 419 | In Stock |
![]() ![]() |
100MG | 605 | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product Name20(S)-Hydroxycholesterol
-
NoteResearch use only, not for human use.
-
Brief Description20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).
-
Description20(S)-Hydroxycholesterol (Standard) is the analytical standard of 20(S)-Hydroxycholesterol. This product is intended for research and analytical applications. 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayWnt/Notch/Hedgehog
-
TargetSmoothened (Smo)
-
RecptorSmo
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number516-72-3
-
Formula Weight402.65
-
Molecular FormulaC27H46O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@](CCCC(C)C)(C)O)[H])[H]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog



related products
-
LY2940680
LY2940680 (Taladegib) is potent Smoothened (SMO) receptor antagonist.
-
PF-5274857 freebase
PF-5274857 is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM).
-
Glasdegib
Glasdegib (PF-04449913) is a potent, orally bioavailable smoothened (SMO) inhibitor with IC50 of 5 nM in the Gli-luciferase reporter assays.