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2-Hydroxychalcone

CAS No. 644-78-0

2-Hydroxychalcone( 2-(2-Hydroxybenzal)Acetophenone )

Catalog No. M21306 CAS No. 644-78-0

2-Hydroxychalcone can be used as antiparasitic hit compounds when Methoxylated.It can?inhibit invasion of triple negative breast cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Hydroxychalcone
  • Note
    Research use only, not for human use.
  • Brief Description
    2-Hydroxychalcone can be used as antiparasitic hit compounds when Methoxylated.It can?inhibit invasion of triple negative breast cancer cells.
  • Description
    2-Hydroxychalcone can be used as antiparasitic hit compounds when Methoxylated.It can?inhibit invasion of triple negative breast cancer cells.
  • In Vitro
    2-Hydroxychalcone inhibits invasion of triple negative breast cancer cells.2-hydroxychalcone inhibits the adhesion of peripheral neutrophils to the endothelial cell monolayers by inhibiting the expression of ICAM-1, VCAM-1, and E-selectin in a concentration-dependent manner.
  • In Vivo
    ——
  • Synonyms
    2-(2-Hydroxybenzal)Acetophenone
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    644-78-0
  • Formula Weight
    224.25
  • Molecular Formula
    C15H12O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (557.41 mM)
  • SMILES
    Oc1c(C=CC(c2ccccc2)=O)cccc1
  • Chemical Name
    2-Hydroxychalcone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim S Y Lee I S Moon A . 2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells[J]. Chemico Biological Interactions 2013 203(3):565-572.
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