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2-Di-1-ASP

CAS No. 2156-29-8

2-Di-1-ASP ( —— )

Catalog No. M22611 CAS No. 2156-29-8

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Di-1-ASP
  • Note
    Research use only, not for human use.
  • Brief Description
    2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA.
  • Description
    2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G4 structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-myc, c-kit87up).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2156-29-8
  • Formula Weight
    366.24
  • Molecular Formula
    C16H19IN2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:24 mg/mL (65.53 mM; Need ultrasonic)
  • SMILES
    [I-].CN(C)c1ccc(\C=C\c2cccc[n+]2C)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889.
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