
2-Di-1-ASP
CAS No. 2156-29-8
2-Di-1-ASP( —— )
Catalog No. M22611 CAS No. 2156-29-8
2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA.
Purity : >98% (HPLC)






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Biological Information
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Product Name2-Di-1-ASP
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NoteResearch use only, not for human use.
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Brief Description2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA.
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Description2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G4 structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-myc, c-kit87up).
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In Vitro2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc).
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2156-29-8
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Formula Weight366.24
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Molecular FormulaC16H19IN2
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Purity>98% (HPLC)
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SolubilityDMSO:24 mg/mL (65.53 mM; Need ultrasonic)
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SMILES[I-].CN(C)c1ccc(\C=C\c2cccc[n+]2C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889.
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