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2-C-beta-Methylguanosine

CAS No. 374750-30-8

2-C-beta-Methylguanosine( —— )

Catalog No. M37882 CAS No. 374750-30-8

2'-C-beta-Methylguanosine (2'-C-Methylguanosine) is a metabolite of the hepatitis C virus nucleotide polymerase inhibitor, BMS-986094, which has antiviral activity and inhibits dengue virus 2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 296 Get Quote
5MG 459 Get Quote
10MG 657 Get Quote
25MG 994 Get Quote
50MG 1371 Get Quote
100MG 1773 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    2-C-beta-Methylguanosine
  • Note
    Research use only, not for human use.
  • Brief Description
    2'-C-beta-Methylguanosine (2'-C-Methylguanosine) is a metabolite of the hepatitis C virus nucleotide polymerase inhibitor, BMS-986094, which has antiviral activity and inhibits dengue virus 2.
  • Description
    2'-C-Methylguanosine (2'-C-beta-Methylguanosine) is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Antiviral
  • Recptor
    Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    374750-30-8
  • Formula Weight
    297.27
  • Molecular Formula
    C11H15N5O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[C@]1(O)[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](CO)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.?
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