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2-Arachidonoylglycerol
CAS No. 53847-30-6
2-Arachidonoylglycerol ( —— )
Catalog No. M26591 CAS No. 53847-30-6
2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 197 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product Name2-Arachidonoylglycerol
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NoteResearch use only, not for human use.
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Brief Description2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.
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Description2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.(In Vitro):The CB1 receptor agonist WIN-55212-2 (3?μM) inhibited forskolin-induced cAMP accumulation, an effect that was reverted by the CB1 antagonist SR-141716 (1?μM) or by pertussis toxin. 2-Arachidonoylglycerol (10?μM) elicited a quantitatively similar inhibition which was also sensitive to SR-141716 and pertussis toxin. This effect occurred with a potency (IC50 = 0.8?μM) consistent with the affinity of 2-Arachidonoylglycerol for CB1 receptors (Ki = 0.7–2.4?μM) and comparable to the potency of anandamide (IC50 = 1.2?μM).
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Synonyms——
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number53847-30-6
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Formula Weight378.6
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Molecular FormulaC23H38O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC(CO)CO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Koolen HH, et al. An antimicrobial diketopiperazine alkaloid and co-metabolites from an endophytic strain of Gliocladium isolated from Strychnos cf. toxifera. Nat Prod Res. 2012 Nov;26(21):2013-9.
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