17-Beta-Estradiol-3,17-Dipropionate

CAS No. 113-38-2

17-Beta-Estradiol-3,17-Dipropionate( Estradiol dipropionate | Estroici | Estronex | Follicyclin P )

Catalog No. M10466 CAS No. 113-38-2

Estradiol dipropionate is a synthetic ester, specifically the 3,17-dipropanoyl ester, of the natural estrogen, estradiol.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    17-Beta-Estradiol-3,17-Dipropionate
  • Note
    Research use only, not for human use.
  • Brief Description
    Estradiol dipropionate is a synthetic ester, specifically the 3,17-dipropanoyl ester, of the natural estrogen, estradiol.
  • Description
    Estradiol dipropionate is a synthetic ester, specifically the 3,17-dipropanoyl ester, of the natural estrogen, estradiol.(In Vivo):Treatment of Estradiol dipropionate (2μg per 100 g; single subcutaneous injection) and Chorionic gonadotropin (10 IU per 100 g; sc; twice a day) for 2 days, levels of β-catenin and GSK-3β in luminal and glandular epithelia are lower in Ovariectomized mice.Treatment of Estradiol dipropionate (2 μg per 100 g; once a week) and Chorionic gonadotropin ((10 IU per 100 g; once a day) for a month, the incidence of atypical endometrial hyperplasia is significantly higher, the level of β-catenin is slightly higher, and the expression of GSK-3β is lower in luminal and glandular epithelia.
  • In Vitro
    ——
  • In Vivo
    Treatment of Estradiol dipropionate (2μg per 100 g; single subcutaneous injection) and Chorionic gonadotropin (10 IU per 100 g; sc; twice a day) for 2 days, levels of β-catenin and GSK-3β in luminal and glandular epithelia are lower in Ovariectomized mice.Treatment of Estradiol dipropionate (2 μg per 100 g; once a week) and Chorionic gonadotropin ((10 IU per 100 g; once a day) for a month, the incidence of atypical endometrial hyperplasia is significantly higher, the level of β-catenin is slightly higher, and the expression of GSK-3β is lower in luminal and glandular epithelia.
  • Synonyms
    Estradiol dipropionate | Estroici | Estronex | Follicyclin P
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    ER
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    113-38-2
  • Formula Weight
    384.52
  • Molecular Formula
    C24H32O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    C[C@@]12[C@@H](OC(CC)=O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(CC)=O)=C4)[C@@]3([H])CC2
  • Chemical Name
    (17beta)-Estra-1,3,5(10)-triene-3,17-diol, dipropanoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Noguchi M, et al.J Vet Med Sci. 2013; 75(3):343-8.
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