12-Distearoyl-sn-glycero-3-phosphoethan( 12-Distearoyl-sn-glycero-3-phosphorylethanolamine | 12-DSPE )

Catalog No. M20070 CAS No. 1069-79-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

12-Distearoyl-sn-glycero-3-phosphoethan
Note

Research use only, not for human use.
Brief Description

12-Distearoyl-sn-glycero-3-phosphorylethanolamine is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats coco butter and sesame oil. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells as well as being involved in metabolism and signaling.
Description

12-Distearoyl-sn-glycero-3-phosphorylethanolamine is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats coco butter and sesame oil. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells as well as being involved in metabolism and signaling.
In Vitro

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE), one of many phosphoethanolamine (PE) lipids, cannot sustain a lamellar form at pH values below ～8.5, the pKa of the ethanolamine moiety.
In Vivo

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Synonyms

12-Distearoyl-sn-glycero-3-phosphorylethanolamine | 12-DSPE
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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1.McCarley RL. Redox-responsive delivery systems. Annu Rev Anal Chem (Palo Alto Calif). 2012;5:391-411.

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