11-O-Galloylbergenin ( —— )

Catalog No. M28172 CAS No. 82958-44-9

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Product Name

11-O-Galloylbergenin
Note

Research use only, not for human use.
Brief Description

11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and it exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.
Description

11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and it exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.11-O-Galloylbergenin shows significant urease inhibitory potential with IC50 value of 38.6±1.5 uM.(In Vivo):11-O-Galloylbergenin (20 and 40 mg/kg) shows analgesic activity against formalin test in rats and 11-O-Galloylbergenin(10-30 mg/kg) exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Antibacterial;Mycobacterium tuberculosis
Research Area

——
Indication

——

CAS Number

82958-44-9
Formula Weight

480.4
Molecular Formula

C21H20O13
Purity

>98% (HPLC)
Solubility

——
SMILES

COc1c(O)cc2C(=O)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](COC(=O)c4cc(O)c(O)c(O)c4)O[C@H]3c2c1O
Chemical Name

——

1.Kesicki EA, et al. Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents. PLoS One. 2016 May 12;11(5):e0155209.

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