1,2-Bis(2-iodoethoxy)ethane

Research use only, not for human use.

1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 and SJF620.

1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 and SJF620. MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively.(In Vitro):1,2-Bis(2-iodoethoxy)ethane is a PROTAC linker, which refers to the PEG composition. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of a series of PROTACs, such as MT802 and SJF620. PROTAC MT802 has a ligand specific for BTK, and a ligand specific to a E3 ligase cereblon (CRBN) connected by polyethylene glycol (PEG) linker 1,2-Bis(2-iodoethoxy)ethane.

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Others

Other Targets

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36839-55-1

370.0

C6H12I2O2

>98% (HPLC)

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ICCOCCOCCI

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(-20℃)

With Ice Pack

≥ 2 years