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(±)-Lisofylline

CAS No. 6493-06-7

(±)-Lisofylline( —— )

Catalog No. M27455 CAS No. 6493-06-7

(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (±)-Lisofylline
  • Note
    Research use only, not for human use.
  • Brief Description
    (±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.
  • Description
    (±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.(In Vivo):(±)-Lisofylline improves survival in this model of hemorrhagic shock in Sprague-Dawley rats.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SMS1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6493-06-7
  • Formula Weight
    280.32
  • Molecular Formula
    C13H20N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (356.74 mM)
  • SMILES
    CC(CCCCN(C(c1c(N2C)ncn1C)=O)C2=O)OCC(CCCCN(C(c1c(N2C)ncn1C)=O)C2=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li YL, et al. Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.Bioorg Med Chem. 2015 Sep 15;23(18):6173-84.
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